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Caveolin-1 regulates chemokine receptor 5-mediated contribution of bone marrow-derived cells to dermal fibrosis

In fibrotic diseases caveolin-1 underexpression in fibroblasts results in collagen overexpression and in monocytes leads to hypermigration. These profibrotic behaviors are blocked by the caveolin-1 scaffolding domain peptide (CSD) which compensates for caveolin-1 deficiency. Monocytes and fibroblast...

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Detalles Bibliográficos
Autores principales:	Lee, Rebecca, Perry, Beth, Heywood, Jonathan, Reese, Charles, Bonner, Michael, Hatfield, Corey M., Silver, Richard M., Visconti, Richard P., Hoffman, Stanley, Tourkina, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052341/ https://www.ncbi.nlm.nih.gov/pubmed/24966836 http://dx.doi.org/10.3389/fphar.2014.00140

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