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Interaction of Apoptotic Cells with Macrophages Upregulates COX-2/PGE(2) and HGF Expression via a Positive Feedback Loop

Recognition of apoptotic cells by macrophages is crucial for resolution of inflammation, immune tolerance, and tissue repair. Cyclooxygenase-2 (COX-2)/prostaglandin E2 (PGE(2)) and hepatocyte growth factor (HGF) play important roles in the tissue repair process. We investigated the characteristics o...

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Detalles Bibliográficos
Autores principales: Byun, Ji Yeon, Youn, Young-So, Lee, Ye-Ji, Choi, Youn-Hee, Woo, So-Yeon, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052493/
https://www.ncbi.nlm.nih.gov/pubmed/24959005
http://dx.doi.org/10.1155/2014/463524

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