Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ß(I) and prooxidant enzyme NADPH oxidase

Blood–brain barrier disruption represents a key feature in hyperglycaemia-aggravated cerebral damage after an ischaemic stroke. Although the underlying mechanisms remain largely unknown, activation of protein kinase C (PKC) is thought to play a critical role. This study examined whether apoptosis of...

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Detalles Bibliográficos
Autores principales: Shao, Beili, Bayraktutan, Ulvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052534/
https://www.ncbi.nlm.nih.gov/pubmed/24936444
http://dx.doi.org/10.1016/j.redox.2014.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052534/
https://www.ncbi.nlm.nih.gov/pubmed/24936444
http://dx.doi.org/10.1016/j.redox.2014.05.005

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