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Hyperglycaemia promotes human brain microvascular endothelial cell apoptosis via induction of protein kinase C-ß(I) and prooxidant enzyme NADPH oxidase
Blood–brain barrier disruption represents a key feature in hyperglycaemia-aggravated cerebral damage after an ischaemic stroke. Although the underlying mechanisms remain largely unknown, activation of protein kinase C (PKC) is thought to play a critical role. This study examined whether apoptosis of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052534/ https://www.ncbi.nlm.nih.gov/pubmed/24936444 http://dx.doi.org/10.1016/j.redox.2014.05.005 |