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Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window

Neuregulin-1 and epidermal growth factor (EGF) are implicated in the pathogenesis of schizophrenia. To test the developmental hypothesis for schizophrenia, we administered these factors to rodent pups, juveniles, and adults and characterized neurobiological and behavioral consequences. These factors...

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Detalles Bibliográficos
Autores principales: Nawa, Hiroyuki, Sotoyama, Hidekazu, Iwakura, Yuriko, Takei, Nobuyuki, Namba, Hisaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052624/
https://www.ncbi.nlm.nih.gov/pubmed/24949465
http://dx.doi.org/10.1155/2014/697935

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