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Enzymatic synthesis of epothilone A glycosides

Epothilones are extremely cytotoxic chemotherapeutic agents with epoxide, thiazole, and ketone groups that share equipotent kinetic similarity with taxol. The in vitro glycosylation catalyzed by uridine diphosphate glucosyltransferase (YjiC) from Bacillus licheniformis generated six novel epothilone...

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Detalles Bibliográficos
Autores principales:	Parajuli, Prakash, Pandey, Ramesh Prasad, Koirala, Niranjan, Yoon, Yeo Joon, Kim, Byung-Gee, Sohng, Jae Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052672/ https://www.ncbi.nlm.nih.gov/pubmed/24949266 http://dx.doi.org/10.1186/s13568-014-0031-1

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