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Identification of temozolomide resistance factors in glioblastoma via integrative miRNA/mRNA regulatory network analysis

Drug resistance is a major issue in the treatment of glioblastoma. Almost all glioblastomas are intrinsically resistant to chemotherapeutic temozolomide (TMZ) or develop resistance during treatment. The interaction networks of microRNAs (miRNAs) and mRNAs likely regulate most biological processes an...

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Detalles Bibliográficos
Autores principales:	Hiddingh, Lotte, Raktoe, Rajiv S., Jeuken, Judith, Hulleman, Esther, Noske, David P., Kaspers, Gertjan J. L., Vandertop, W. Peter, Wesseling, Pieter, Wurdinger, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052714/ https://www.ncbi.nlm.nih.gov/pubmed/24919120 http://dx.doi.org/10.1038/srep05260

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