How to build segregation complexes in bacteria: Use bridges

In this issue of Genes & Development, Graham and colleagues (pp. 1228–1238) examine how ParBs, which bind to prokaryotic centromere-like partition sites, spread into nearby nonspecific DNA and assemble into higher-order protein–DNA complexes. Spreading is accomplished by looping rather than one-...

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Detalles Bibliográficos
Autor principal: Funnell, Barbara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052760/
https://www.ncbi.nlm.nih.gov/pubmed/24888585
http://dx.doi.org/10.1101/gad.244517.114
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author Funnell, Barbara E.
author_facet Funnell, Barbara E.
author_sort Funnell, Barbara E.
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description In this issue of Genes & Development, Graham and colleagues (pp. 1228–1238) examine how ParBs, which bind to prokaryotic centromere-like partition sites, spread into nearby nonspecific DNA and assemble into higher-order protein–DNA complexes. Spreading is accomplished by looping rather than one-dimensional filamentation, thereby compacting the DNA into an extensively bridged complex.
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spelling pubmed-40527602014-12-01 How to build segregation complexes in bacteria: Use bridges Funnell, Barbara E. Genes Dev Perspective In this issue of Genes & Development, Graham and colleagues (pp. 1228–1238) examine how ParBs, which bind to prokaryotic centromere-like partition sites, spread into nearby nonspecific DNA and assemble into higher-order protein–DNA complexes. Spreading is accomplished by looping rather than one-dimensional filamentation, thereby compacting the DNA into an extensively bridged complex. Cold Spring Harbor Laboratory Press 2014-06-01 /pmc/articles/PMC4052760/ /pubmed/24888585 http://dx.doi.org/10.1101/gad.244517.114 Text en © 2014 Funnell; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Perspective
Funnell, Barbara E.
How to build segregation complexes in bacteria: Use bridges
title How to build segregation complexes in bacteria: Use bridges
title_full How to build segregation complexes in bacteria: Use bridges
title_fullStr How to build segregation complexes in bacteria: Use bridges
title_full_unstemmed How to build segregation complexes in bacteria: Use bridges
title_short How to build segregation complexes in bacteria: Use bridges
title_sort how to build segregation complexes in bacteria: use bridges
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052760/
https://www.ncbi.nlm.nih.gov/pubmed/24888585
http://dx.doi.org/10.1101/gad.244517.114
work_keys_str_mv AT funnellbarbarae howtobuildsegregationcomplexesinbacteriausebridges

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