Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing

Tumor metastasis remains the major cause of cancer-related death, but its molecular basis is still not well understood. Here we uncovered a splicing-mediated pathway that is essential for breast cancer metastasis. We show that the RNA-binding protein heterogeneous nuclear ribonucleoprotein M (hnRNPM...

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Detalles Bibliográficos
Autores principales: Xu, Yilin, Gao, Xin D., Lee, Jae-Hyung, Huang, Huilin, Tan, Haiyan, Ahn, Jaegyoon, Reinke, Lauren M., Peter, Marcus E., Feng, Yue, Gius, David, Siziopikou, Kalliopi P., Peng, Junmin, Xiao, Xinshu, Cheng, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052765/
https://www.ncbi.nlm.nih.gov/pubmed/24840202
http://dx.doi.org/10.1101/gad.241968.114

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