Cargando…
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo
Autophagy is crucial for cellular homeostasis and plays important roles in tumorigenesis. FIP200 (FAK family-interacting protein of 200 kDa) is an essential autophagy gene required for autophagy induction, functioning in the ULK1–ATG13–FIP200 complex. Our previous studies showed that conditional kno...
Autores principales: | Wei, Huijun, Wang, Chenran, Croce, Carlo M., Guan, Jun-Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052766/ https://www.ncbi.nlm.nih.gov/pubmed/24888590 http://dx.doi.org/10.1101/gad.237354.113 |
Ejemplares similares
-
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
por: Wang, Chenran, et al.
Publicado: (2016) -
Correction: Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
por: Wang, Chenran, et al.
Publicado: (2016) -
ZZ-dependent regulation of p62/SQSTM1 in autophagy
por: Zhang, Yi, et al.
Publicado: (2018) -
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair
por: Hewitt, Graeme, et al.
Publicado: (2016) -
Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy
por: Manirujjaman, M., et al.
Publicado: (2020)