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Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction

BACKGROUND: Probucol has been shown to prevent cerebral capillary disturbances characterized by blood-to-brain extravasation of plasma derived proteins and neurovascular inflammation in mice maintained on western-styled diets for 12 weeks. However the effect of probucol on capillary integrity in agi...

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Detalles Bibliográficos
Autores principales: Takechi, Ryusuke, Pallebage-Gamarallage, Menuka M, Lam, Virginie, Giles, Corey, Mamo, John CL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052824/
https://www.ncbi.nlm.nih.gov/pubmed/24890126
http://dx.doi.org/10.1186/1476-511X-13-91