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Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction
BACKGROUND: Probucol has been shown to prevent cerebral capillary disturbances characterized by blood-to-brain extravasation of plasma derived proteins and neurovascular inflammation in mice maintained on western-styled diets for 12 weeks. However the effect of probucol on capillary integrity in agi...
Autores principales: | Takechi, Ryusuke, Pallebage-Gamarallage, Menuka M, Lam, Virginie, Giles, Corey, Mamo, John CL |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052824/ https://www.ncbi.nlm.nih.gov/pubmed/24890126 http://dx.doi.org/10.1186/1476-511X-13-91 |
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