Immunization with the Recombinant Cholera Toxin B Fused to Fimbria 2 Protein Protects against Bordetella pertussis Infection

This study examined the immunogenic properties of the fusion protein fimbria 2 of Bordetella pertussis (Fim2)—cholera toxin B subunit (CTB) in the intranasal murine model of infection. To this end B. pertussis Fim2 coding sequence was cloned downstream of the cholera toxin B subunit coding sequence....

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Detalles Bibliográficos
Autores principales: Olivera, Noelia, Castuma, Celina E., Hozbor, Daniela, Gaillard, María E., Rumbo, Martín, Gómez, Ricardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052895/
https://www.ncbi.nlm.nih.gov/pubmed/24982881
http://dx.doi.org/10.1155/2014/421486

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