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A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion

INTRODUCTION: Tumor cell migration and invasion are critical initiation steps in the process of breast cancer metastasis, the primary cause of breast cancer morbidity and death. Here we investigated the role of p21Cip1 (p21), a member of the core cell cycle machinery, in transforming growth factor-b...

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Detalles Bibliográficos
Autores principales: Dai, Meiou, Al-Odaini, Amal A, Arakelian, Ani, Rabbani, Shafaat A, Ali, Suhad, Lebrun, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053104/
https://www.ncbi.nlm.nih.gov/pubmed/22995475
http://dx.doi.org/10.1186/bcr3322