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YAP-Hippo signalling downstream of leukemia inhibitory factor receptor: implications for breast cancer

The proto-oncogenes YAP and TAZ have previously gained much attention as downstream effectors of Hippo tumour suppressor signalling. While the regulation of YAP/TAZ by MST/LATS kinases is reasonably well understood, the nature of factors functioning upstream of MST/LATS is yet to be elucidated in de...

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Detalles Bibliográficos
Autor principal: Hergovich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053130/
https://www.ncbi.nlm.nih.gov/pubmed/23216692
http://dx.doi.org/10.1186/bcr3349

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