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Who do they think they are? Wnt-responsive cells reveal their family trees

The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are startin...

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Detalles Bibliográficos
Autores principales: Ordonez, Liliana, Smalley, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053131/
https://www.ncbi.nlm.nih.gov/pubmed/23227978
http://dx.doi.org/10.1186/bcr3351
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author Ordonez, Liliana
Smalley, Matthew J
author_facet Ordonez, Liliana
Smalley, Matthew J
author_sort Ordonez, Liliana
collection PubMed
description The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem.
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spelling pubmed-40531312014-06-12 Who do they think they are? Wnt-responsive cells reveal their family trees Ordonez, Liliana Smalley, Matthew J Breast Cancer Res Viewpoint The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem. BioMed Central 2012 2012-12-10 /pmc/articles/PMC4053131/ /pubmed/23227978 http://dx.doi.org/10.1186/bcr3351 Text en Copyright © 2012 BioMed Central Ltd
spellingShingle Viewpoint
Ordonez, Liliana
Smalley, Matthew J
Who do they think they are? Wnt-responsive cells reveal their family trees
title Who do they think they are? Wnt-responsive cells reveal their family trees
title_full Who do they think they are? Wnt-responsive cells reveal their family trees
title_fullStr Who do they think they are? Wnt-responsive cells reveal their family trees
title_full_unstemmed Who do they think they are? Wnt-responsive cells reveal their family trees
title_short Who do they think they are? Wnt-responsive cells reveal their family trees
title_sort who do they think they are? wnt-responsive cells reveal their family trees
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053131/
https://www.ncbi.nlm.nih.gov/pubmed/23227978
http://dx.doi.org/10.1186/bcr3351
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