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Who do they think they are? Wnt-responsive cells reveal their family trees
The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are startin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053131/ https://www.ncbi.nlm.nih.gov/pubmed/23227978 http://dx.doi.org/10.1186/bcr3351 |
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author | Ordonez, Liliana Smalley, Matthew J |
author_facet | Ordonez, Liliana Smalley, Matthew J |
author_sort | Ordonez, Liliana |
collection | PubMed |
description | The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem. |
format | Online Article Text |
id | pubmed-4053131 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40531312014-06-12 Who do they think they are? Wnt-responsive cells reveal their family trees Ordonez, Liliana Smalley, Matthew J Breast Cancer Res Viewpoint The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem. BioMed Central 2012 2012-12-10 /pmc/articles/PMC4053131/ /pubmed/23227978 http://dx.doi.org/10.1186/bcr3351 Text en Copyright © 2012 BioMed Central Ltd |
spellingShingle | Viewpoint Ordonez, Liliana Smalley, Matthew J Who do they think they are? Wnt-responsive cells reveal their family trees |
title | Who do they think they are? Wnt-responsive cells reveal their family trees |
title_full | Who do they think they are? Wnt-responsive cells reveal their family trees |
title_fullStr | Who do they think they are? Wnt-responsive cells reveal their family trees |
title_full_unstemmed | Who do they think they are? Wnt-responsive cells reveal their family trees |
title_short | Who do they think they are? Wnt-responsive cells reveal their family trees |
title_sort | who do they think they are? wnt-responsive cells reveal their family trees |
topic | Viewpoint |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053131/ https://www.ncbi.nlm.nih.gov/pubmed/23227978 http://dx.doi.org/10.1186/bcr3351 |
work_keys_str_mv | AT ordonezliliana whodotheythinktheyarewntresponsivecellsrevealtheirfamilytrees AT smalleymatthewj whodotheythinktheyarewntresponsivecellsrevealtheirfamilytrees |