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A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue
INTRODUCTION: Immunohistochemical Ki67 labelling index (Ki67 LI) reflects proliferative activity and is a potential prognostic/predictive marker of breast cancer. However, its clinical utility is hindered by the lack of standardized measurement methodologies. Besides tissue heterogeneity aspects, th...
Autores principales: | Laurinavicius, Arvydas, Plancoulaine, Benoit, Laurinaviciene, Aida, Herlin, Paulette, Meskauskas, Raimundas, Baltrusaityte, Indra, Besusparis, Justinas, Dasevicius, Darius, Elie, Nicolas, Iqbal, Yasir, Bor, Catherine, Ellis, Ian O |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053156/ https://www.ncbi.nlm.nih.gov/pubmed/24708745 http://dx.doi.org/10.1186/bcr3639 |
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