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Outsmarting cancer: the power of hybrid genomic/proteomic biomarkers to predict drug response

A recent study by Niepel and colleagues describes a novel approach to predicting response to targeted anti-cancer therapies. The authors used biochemical profiling of signaling activity in basal and ligand-stimulated states for a panel of receptor and intracellular kinases to develop predictive mode...

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Detalles Bibliográficos
Autores principales: Rexer, Brent N, Arteaga, Carlos L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053204/
https://www.ncbi.nlm.nih.gov/pubmed/25032256
http://dx.doi.org/10.1186/bcr3635