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Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways

INTRODUCTION: Metastasis is the main cause of breast cancer morbidity and mortality. Processes that allow for tumor cell migration and invasion are important therapeutic targets. Here we demonstrate that receptor-interacting protein kinase 2 (RIP2), a kinase known to be involved in inflammatory proc...

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Detalles Bibliográficos
Autores principales: Singel, Stina M, Batten, Kimberly, Cornelius, Crystal, Jia, Gaoxiang, Fasciani, Gail, Barron, Summer L, Wright, Woodring E, Shay, Jerry W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053227/
https://www.ncbi.nlm.nih.gov/pubmed/24642040
http://dx.doi.org/10.1186/bcr3629

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