Cargando…

Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion

INTRODUCTION: Deregulation of the cell cycle machinery is often found in human cancers. Modulations in the cell cycle regulator function and expression result not only in proliferative advantages, but also lead to tumor progression and invasiveness of the cancer. In particular, cyclin D1 and p21 are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Meiou, Al-Odaini, Amal A, Fils-Aimé, Nadège, Villatoro, Manuel A, Guo, Jimin, Arakelian, Ani, Rabbani, Shafaat A, Ali, Suhad, Lebrun, Jean Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053239/ https://www.ncbi.nlm.nih.gov/pubmed/23786849 http://dx.doi.org/10.1186/bcr3441

Ejemplares similares

Erratum to: Cyclin D1 cooperates with p21 to regulate TGFβ-mediated breast cancer cell migration and tumor local invasion
por: Dai, Meiou, et al.
Publicado: (2017)

A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion
por: Dai, Meiou, et al.
Publicado: (2012)

Erratum to: A novel function for p21 Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion
por: Dai, Meiou, et al.
Publicado: (2017)

Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes
por: Guo, Jimin, et al.
Publicado: (2014)

CDK4 regulates cancer stemness and is a novel therapeutic target for triple-negative breast cancer
por: Dai, Meiou, et al.
Publicado: (2016)

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity
por: Yan, Gang, et al.
Publicado: (2021)

LRP5 knockdown: effect on prostate cancer invasion growth and skeletal metastasis in vitro and in vivo
por: Rabbani, Shafaat A, et al.
Publicado: (2013)

S‐adenosylmethionine in combination with decitabine shows enhanced anti‐cancer effects in repressing breast cancer growth and metastasis
por: Mahmood, Niaz, et al.
Publicado: (2020)

An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis
por: Mahmood, Niaz, et al.
Publicado: (2020)

Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer
por: Tian, Jun, et al.
Publicado: (2017)

DNA methylation signatures of Prostate Cancer in peripheral T-cells
por: Mehdi, Ali, et al.
Publicado: (2020)

Co-Targeting Luminal B Breast Cancer with S-Adenosylmethionine and Immune Checkpoint Inhibitor Reduces Primary Tumor Growth and Progression, and Metastasis to Lungs and Bone
por: Mehdi, Ali, et al.
Publicado: (2022)

uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions
por: Mahmood, Niaz, et al.
Publicado: (2020)

S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications
por: Parashar, Surabhi, et al.
Publicado: (2015)

Enhanced Anticancer Effect of a Combination of S-adenosylmethionine (SAM) and Immune Checkpoint Inhibitor (ICPi) in a Syngeneic Mouse Model of Advanced Melanoma
por: Mehdi, Ali, et al.
Publicado: (2020)

Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications
por: Mahmood, Niaz, et al.
Publicado: (2017)

Combined in vitro/in vivo genome-wide CRISPR screens in triple negative breast cancer identify cancer stemness regulators in paclitaxel resistance
por: Yan, Gang, et al.
Publicado: (2023)

DNA methylation signatures of breast cancer in peripheral T-cells
por: Parashar, Surabhi, et al.
Publicado: (2018)

A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness
por: Cheishvili, David, et al.
Publicado: (2015)

In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
por: Dai, Meiou, et al.
Publicado: (2021)

Transforming Growth Factor-beta Regulation of Ephrin Type-A Receptor 4 Signaling in Breast Cancer Cellular Migration
por: Hachim, Ibrahim Y., et al.
Publicado: (2017)

Author Correction: Transforming Growth Factor-beta Regulation of Ephrin Type-A Receptor 4 Signaling in Breast Cancer Cellular Migration
por: Hachim, Ibrahim Y., et al.
Publicado: (2022)

Prolactin receptor-driven combined luminal and epithelial differentiation in breast cancer restricts plasticity, stemness, tumorigenesis and metastasis
por: Shams, Anwar, et al.
Publicado: (2021)

Dasatinib sensitises triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells
por: Tian, Jun, et al.
Publicado: (2018)

Concomitant Expression of Prolactin Receptor and TGFβ Receptors in Breast Cancer: Association with Less Aggressive Phenotype and Favorable Patient Outcome
por: Hachim, Ibrahim Y., et al.
Publicado: (2019)

The relationship between early weight loss and weight loss maintenance with naltrexone-bupropion therapy
por: le Roux, Carel W., et al.
Publicado: (2022)

The leukemia inhibitory factor (LIF) and p21 mediate the TGFβ tumor suppressive effects in human cutaneous melanoma
por: Humbert, Laure, et al.
Publicado: (2015)

DNA Methylation Readers and Cancer: Mechanistic and Therapeutic Applications
por: Mahmood, Niaz, et al.
Publicado: (2019)

Role of Methylation in Pro- and Anti-Cancer Immunity
por: Mehdi, Ali, et al.
Publicado: (2021)

Fibrinolytic System and Cancer: Diagnostic and Therapeutic Applications
por: Mahmood, Niaz, et al.
Publicado: (2021)

Cyclin dependent kinase 14 as a paclitaxel-resistant marker regulated by the TGF-β signaling pathway in human ovarian cancer
por: Guan, Wencai, et al.
Publicado: (2023)

Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications
por: Mahmood, Niaz, et al.
Publicado: (2018)

The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis
por: Lebrun, Jean-Jacques
Publicado: (2012)

Cyclin D1, cyclin E, and p21 have no apparent prognostic value in anal carcinomas treated by radiotherapy with or without chemotherapy
por: Allal, A S, et al.
Publicado: (2004)

Terminal differentiation and anti-tumorigenic effects of prolactin in breast cancer
por: Ali, Suhad, et al.
Publicado: (2022)

CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target: Role of CPSF6 in Breast Cancer
por: Binothman, Najat, et al.
Publicado: (2017)

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding
por: Faber, Erik B., et al.
Publicado: (2023)

P21-dependent G (1) arrest with downregulation of cyclin D1 and upregulation of cyclin E by the histone deacetylase inhibitor FR901228
por: Sandor, V, et al.
Publicado: (2000)

Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients
por: Bahnassy, Abeer A, et al.
Publicado: (2004)

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability
por: Dardalhon-Cuménal, Delphine, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s7qifh4t8q9htok400hifd9ld4