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METFORMIN: an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents – study protocol of a randomized controlled study
BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the risk of diabetes mellitus type 2. To prevent these complications, lifestyle intervention is the corner stone in treatment. However, long-term efficacy of lifestyle intervention is questionable. In additi...
Autores principales: | van der Aa, Marloes P, Elst, Marieke AJ, van Mil, Edgar GAH, Knibbe, Catherijne AJ, van der Vorst, Marja MJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053305/ https://www.ncbi.nlm.nih.gov/pubmed/24899137 http://dx.doi.org/10.1186/1745-6215-15-207 |
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