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Involvement of Increased Endogenous Asymmetric Dimethylarginine in the Hepatic Endoplasmic Reticulum Stress of Type 2 Diabetic Rats

OBJECTIVE: Increasing evidence suggested that endoplasmic reticulum (ER) stress contributes to insulin resistance, which plays an important role in the development of type 2 diabetes mellitus (T2DM). Accumulation of endogenous nitric oxide synthase (NOS) inhibitor, asymmetric dimethylarginine (ADMA)...

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Detalles Bibliográficos
Autores principales: Leng, Yi-Ping, Qiu, Ni, Fang, Wei-jin, Zhang, Mei, He, Zhi-Min, Xiong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053342/
https://www.ncbi.nlm.nih.gov/pubmed/24918756
http://dx.doi.org/10.1371/journal.pone.0097125