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DP-b99 Modulates Matrix Metalloproteinase Activity and Neuronal Plasticity

DP-b99 is a membrane-activated chelator of zinc and calcium ions, recently proposed as a therapeutic agent. Matrix metalloproteinases (MMPs) are zinc-dependent extracellularly operating proteases that might contribute to synaptic plasticity, learning and memory under physiological conditions. In exc...

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Detalles Bibliográficos
Autores principales:	Yeghiazaryan, Marine, Rutkowska-Wlodarczyk, Izabela, Konopka, Anna, Wilczyński, Grzegorz M., Melikyan, Armenuhi, Korkotian, Eduard, Kaczmarek, Leszek, Figiel, Izabela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053404/ https://www.ncbi.nlm.nih.gov/pubmed/24918931 http://dx.doi.org/10.1371/journal.pone.0099789

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