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Roles for Human Papillomavirus Type 16 L1 Cysteine Residues 161, 229, and 379 in Genome Encapsidation and Capsid Stability

Human papillomavirus (HPV) capsids are formed through a network of inter- and intra-pentameric hydrophobic interactions and disulfide bonds. 72 pentamers of the major capsid protein, L1, and an unknown amount of the minor capsid protein, L2, form the structure of the capsid. There are 12 conserved L...

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Detalles Bibliográficos
Autores principales: Ryndock, Eric J., Conway, Michael J., Alam, Samina, Gul, Sana, Murad, Sheeba, Christensen, Neil D., Meyers, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053435/
https://www.ncbi.nlm.nih.gov/pubmed/24918586
http://dx.doi.org/10.1371/journal.pone.0099488