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Development of a Novel Multiplex PCR Assay to Detect Functional Subtypes of KIR3DL1 Alleles

Among NK cell receptor-ligand partnerships, KIR3DL1 and HLA-Bw4 demonstrate the greatest diversity; permutations of their allelic combinations titrate NK reactivity. Balancing selection has maintained distinct subtypes of KIR3DL1 alleles in global populations, implying that each may provide unique f...

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Detalles Bibliográficos
Autores principales:	Boudreau, Jeanette E., Le Luduec, Jean-Benoît, Hsu, Katharine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053526/ https://www.ncbi.nlm.nih.gov/pubmed/24919192 http://dx.doi.org/10.1371/journal.pone.0099543

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