The tumor suppressor p53 connects ribosome biogenesis to cell cycle control: a double-edged sword

Since its first description more than 30 years ago p53 has become a paradigm for a protein with versatile functions. P53 sensitizes a large variety of genetic alterations and has been entitled the guardian of the genome. Stabilization of p53 upon DNA damage is accompanied by a complex pattern of mod...

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Detalles Bibliográficos
Autores principales: Hölzel, Michael, Burger, Kaspar, Mühl, Bastian, Orban, Mathias, Kellner, Markus, Eick, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053546/
https://www.ncbi.nlm.nih.gov/pubmed/21293052

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