Cargando…

The anabolic catabolic transforming agent (ACTA) espindolol increases muscle mass and decreases fat mass in old rats

BACKGROUND: Sarcopenia, the age-related, progressive loss of skeletal muscle mass, strength, and function, is a considerable socioeconomic burden by increasing risks of falls, fractures, and frailty. Moreover, sarcopenic patients are often obese and therapeutic options are very limited. METHODS: Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pötsch, Mareike S., Tschirner, Anika, Palus, Sandra, von Haehling, Stephan, Doehner, Wolfram, Beadle, John, Coats, Andrew J. S., Anker, Stefan D., Springer, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053568/ https://www.ncbi.nlm.nih.gov/pubmed/24272787 http://dx.doi.org/10.1007/s13539-013-0125-7

Ejemplares similares

MT‐102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia
por: Pötsch, Mareike S., et al.
Publicado: (2020)

Ursodeoxycholic acid treatment in a rat model of cancer cachexia
por: Tschirner, Anika, et al.
Publicado: (2011)

Febuxostat improves outcome in a rat model of cancer cachexia
por: Konishi, Masaaki, et al.
Publicado: (2015)

Higher serum phosphorus is associated with catabolic/anabolic imbalance in heart failure
por: Rozentryt, Piotr, et al.
Publicado: (2015)

Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non‐small cell lung cancer or colorectal cancer: a randomized, double‐blind, placebo‐controlled, international multicentre phase II study (the ACT‐ONE trial)
por: Stewart Coats, Andrew J., et al.
Publicado: (2016)

Megestrol acetate improves cardiac function in a model of cancer cachexia‐induced cardiomyopathy by autophagic modulation
por: Musolino, Vincenzo, et al.
Publicado: (2016)

IGF-1 treatment reduces weight loss and improves outcome in a rat model of cancer cachexia
por: Schmidt, Katja, et al.
Publicado: (2011)

Six1 is down‐regulated in end‐stage human dilated cardiomyopathy independently of Ezh2
por: Tschirner, Anika, et al.
Publicado: (2015)

Blocking myostatin: muscle mass equals muscle strength?
por: Anker, Markus S., et al.
Publicado: (2020)

Cachexia in heart disease: highlights from the ESC 2010
por: Kung, Thomas, et al.
Publicado: (2011)

Bile acids for cachexia therapy: Reply to the letter by Shailendra Kapoor: Ursodeoxycholic acid and its emerging role in attenuation of tumor growth in gastrointestinal malignancies
por: Tschirner, Anika, et al.
Publicado: (2012)

Influence of cancer cachexia on drug liver metabolism and renal elimination in rats
por: Cvan Trobec, Katja, et al.
Publicado: (2015)

The Use of Anabolic Agents in Catabolic States
por: Demling, Robert
Publicado: (2007)

The 10th year of the Journal of Cachexia, Sarcopenia and Muscle
por: Anker, Markus S., et al.
Publicado: (2020)

Body mass index and prognosis in patients hospitalized with acute exacerbation of chronic obstructive pulmonary disease
por: Lainscak, Mitja, et al.
Publicado: (2011)

Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis
por: Kim, Hyeonkyeong, et al.
Publicado: (2015)

Vibration paradox in orthodontics: Anabolic and catabolic effects
por: Alikhani, Mani, et al.
Publicado: (2018)

Coupled catabolism and anabolism in autocatalytic RNA sets
por: Arsène, Simon, et al.
Publicado: (2018)

Muscle wasting: an overview of recent developments in basic research
por: Palus, Sandra, et al.
Publicado: (2014)

The erythropoietin‐derived peptide ARA 284 reduces tissue wasting and improves survival in a rat model of cancer cachexia
por: Palus, Sandra, et al.
Publicado: (2022)

Cardiac cachexia: hic et nunc
por: Loncar, Goran, et al.
Publicado: (2016)

Chronic Drought Decreases Anabolic and Catabolic BVOC Emissions of Quercus pubescens in a Mediterranean Forest
por: Saunier, Amélie, et al.
Publicado: (2017)

The obesity paradox in chronic disease: facts and numbers
por: Lainscak, Mitja, et al.
Publicado: (2012)

The Role of Anabolic Hormones for Wound Healing in Catabolic States
por: Demling, Robert H.
Publicado: (2005)

Glucose-Induced Hemodynamic and Metabolic Response of Skeletal Muscle in Heart Failure Patients with Reduced vs. Preserved Ejection Fraction—A Pilot Study
por: Boschmann, Michael, et al.
Publicado: (2022)

Airway microbiota signals anabolic and catabolic remodeling in the transplanted lung
por: Mouraux, Stéphane, et al.
Publicado: (2018)

P2Y Receptors in Bone - Anabolic, Catabolic, or Both?
por: Zhou, Yuhan, et al.
Publicado: (2022)

Influence of essential amino acids on muscle mass and muscle strength in patients with cerebral stroke during early rehabilitation: protocol and rationale of a randomized clinical trial (AMINO-Stroke Study)
por: Scherbakov, Nadja, et al.
Publicado: (2016)

Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies
por: Ebner, Nicole, et al.
Publicado: (2014)

Estimating fat mass in heart failure patients
por: Trippel, Tobias Daniel, et al.
Publicado: (2016)

Formoterol in the treatment of experimental cancer cachexia: effects on heart function
por: Toledo, Míriam, et al.
Publicado: (2014)

Recent developments in the treatment of cachexia: highlights from the 6th Cachexia Conference
por: Ebner, Nicole, et al.
Publicado: (2012)

Do we need a reference standard for the muscle mass measurements?
por: Scherbakov, Nadja, et al.
Publicado: (2018)

Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages
por: Ströbel, Simon, et al.
Publicado: (2010)

RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes
por: McDermott, B.T., et al.
Publicado: (2016)

Pharmacological inhibition of tumor anabolism and host catabolism as a cancer therapy
por: Schcolnik-Cabrera, Alejandro, et al.
Publicado: (2021)

Ferric carboxymaltose for the treatment of iron‐deficient heart failure patients: a systematic review and meta‐analysis
por: Khan, Muhammad Shahzeb, et al.
Publicado: (2020)

Leukocyte Redistribution: Effects of Beta Blockers in Patients with Chronic Heart Failure
por: von Haehling, Stephan, et al.
Publicado: (2009)

Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes
por: Alvarez, Karl, et al.
Publicado: (2014)

Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes
por: Gibb, Andrew A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_g7pt8faf75ofm08pb9knelm5rp