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Quantitative reconstruction of leukocyte subsets using DNA methylation

BACKGROUND: Cell lineage-specific DNA methylation patterns distinguish normal human leukocyte subsets and can be used to detect and quantify these subsets in peripheral blood. We have developed an approach that uses DNA methylation to simultaneously quantify multiple leukocyte subsets, enabling inve...

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Detalles Bibliográficos
Autores principales: Accomando, William P, Wiencke, John K, Houseman, E Andres, Nelson, Heather H, Kelsey, Karl T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053693/
https://www.ncbi.nlm.nih.gov/pubmed/24598480
http://dx.doi.org/10.1186/gb-2014-15-3-r50