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Genome-wide analysis of functional sirtuin chromatin targets in yeast
BACKGROUND: The sirtuins are a conserved family of NAD(+)-dependent histone/protein deacetylases that regulate numerous cellular processes, including heterochromatin formation and transcription. Multiple sirtuins are encoded by each eukaryotic genome, raising the possibility of cooperativity or func...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053722/ https://www.ncbi.nlm.nih.gov/pubmed/23710766 http://dx.doi.org/10.1186/gb-2013-14-5-r48 |