Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome

BACKGROUND: X-chromosome inactivation (XCI) results in the silencing of most genes on one X chromosome, yielding mono-allelic expression in individual cells. However, random XCI results in expression of both alleles in most females. Allelic imbalances have been used genome-wide to detect mono-alleli...

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Detalles Bibliográficos
Autores principales: Cotton, Allison M, Ge, Bing, Light, Nicholas, Adoue, Veronique, Pastinen, Tomi, Brown, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053723/
https://www.ncbi.nlm.nih.gov/pubmed/24176135
http://dx.doi.org/10.1186/gb-2013-14-11-r122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053723/
https://www.ncbi.nlm.nih.gov/pubmed/24176135
http://dx.doi.org/10.1186/gb-2013-14-11-r122

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