DDIG-in: discriminating between disease-associated and neutral non-frameshifting micro-indels

Micro-indels (insertions or deletions shorter than 21 bps) constitute the second most frequent class of human gene mutation after single nucleotide variants. Despite the relative abundance of non-frameshifting indels, their damaging effect on protein structure and function has gone largely unstudied...

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Detalles Bibliográficos
Autores principales: Zhao, Huiying, Yang, Yuedong, Lin, Hai, Zhang, Xinjun, Mort, Matthew, Cooper, David N, Liu, Yunlong, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053752/
https://www.ncbi.nlm.nih.gov/pubmed/23497682
http://dx.doi.org/10.1186/gb-2013-14-3-r23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053752/
https://www.ncbi.nlm.nih.gov/pubmed/23497682
http://dx.doi.org/10.1186/gb-2013-14-3-r23

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