Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

BACKGROUND: DNA methylation and the Polycomb repression system are epigenetic mechanisms that play important roles in maintaining transcriptional repression. Recent evidence suggests that DNA methylation can attenuate the binding of Polycomb protein components to chromatin and thus plays a role in d...

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Detalles Bibliográficos
Autores principales: Reddington, James P, Perricone, Sara M, Nestor, Colm E, Reichmann, Judith, Youngson, Neil A, Suzuki, Masako, Reinhardt, Diana, Dunican, Donncha S, Prendergast, James G, Mjoseng, Heidi, Ramsahoye, Bernard H, Whitelaw, Emma, Greally, John M, Adams, Ian R, Bickmore, Wendy A, Meehan, Richard R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053768/
https://www.ncbi.nlm.nih.gov/pubmed/23531360
http://dx.doi.org/10.1186/gb-2013-14-3-r25

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