Characterizing 5-methylcytosine in the mammalian epitranscriptome

The post-transcriptional modification 5-methylcytosine (m(5)C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m(5)C RNA methylome. We also discuss the potential functions of m(5)C in RNA and compare them to 6-methyladenosine modi...

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Detalles Bibliográficos
Autores principales: Hussain, Shobbir, Aleksic, Jelena, Blanco, Sandra, Dietmann, Sabine, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053770/
https://www.ncbi.nlm.nih.gov/pubmed/24286375
http://dx.doi.org/10.1186/gb4143
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author Hussain, Shobbir
Aleksic, Jelena
Blanco, Sandra
Dietmann, Sabine
Frye, Michaela
author_facet Hussain, Shobbir
Aleksic, Jelena
Blanco, Sandra
Dietmann, Sabine
Frye, Michaela
author_sort Hussain, Shobbir
collection PubMed
description The post-transcriptional modification 5-methylcytosine (m(5)C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m(5)C RNA methylome. We also discuss the potential functions of m(5)C in RNA and compare them to 6-methyladenosine modifications.
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spelling pubmed-40537702014-06-12 Characterizing 5-methylcytosine in the mammalian epitranscriptome Hussain, Shobbir Aleksic, Jelena Blanco, Sandra Dietmann, Sabine Frye, Michaela Genome Biol Review The post-transcriptional modification 5-methylcytosine (m(5)C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m(5)C RNA methylome. We also discuss the potential functions of m(5)C in RNA and compare them to 6-methyladenosine modifications. BioMed Central 2013 2013-11-29 /pmc/articles/PMC4053770/ /pubmed/24286375 http://dx.doi.org/10.1186/gb4143 Text en Copyright © 2013 BioMed Central Ltd.
spellingShingle Review
Hussain, Shobbir
Aleksic, Jelena
Blanco, Sandra
Dietmann, Sabine
Frye, Michaela
Characterizing 5-methylcytosine in the mammalian epitranscriptome
title Characterizing 5-methylcytosine in the mammalian epitranscriptome
title_full Characterizing 5-methylcytosine in the mammalian epitranscriptome
title_fullStr Characterizing 5-methylcytosine in the mammalian epitranscriptome
title_full_unstemmed Characterizing 5-methylcytosine in the mammalian epitranscriptome
title_short Characterizing 5-methylcytosine in the mammalian epitranscriptome
title_sort characterizing 5-methylcytosine in the mammalian epitranscriptome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053770/
https://www.ncbi.nlm.nih.gov/pubmed/24286375
http://dx.doi.org/10.1186/gb4143
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AT dietmannsabine characterizing5methylcytosineinthemammalianepitranscriptome
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