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Characterizing 5-methylcytosine in the mammalian epitranscriptome

The post-transcriptional modification 5-methylcytosine (m(5)C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m(5)C RNA methylome. We also discuss the potential functions of m(5)C in RNA and compare them to 6-methyladenosine modi...

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Detalles Bibliográficos
Autores principales:	Hussain, Shobbir, Aleksic, Jelena, Blanco, Sandra, Dietmann, Sabine, Frye, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053770/ https://www.ncbi.nlm.nih.gov/pubmed/24286375 http://dx.doi.org/10.1186/gb4143

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