Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs

BACKGROUND: Sequence specific RNA binding proteins are important regulators of gene expression. Several related crosslinking-based, high-throughput sequencing methods, including PAR-CLIP, have recently been developed to determine direct binding sites of global protein-RNA interactions. However, no s...

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Detalles Bibliográficos
Autores principales: Friedersdorf, Matthew B, Keene, Jack D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053780/
https://www.ncbi.nlm.nih.gov/pubmed/24393468
http://dx.doi.org/10.1186/gb-2014-15-1-r2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053780/
https://www.ncbi.nlm.nih.gov/pubmed/24393468
http://dx.doi.org/10.1186/gb-2014-15-1-r2

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