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Advancing the functional utility of PAR-CLIP by quantifying background binding to mRNAs and lncRNAs
BACKGROUND: Sequence specific RNA binding proteins are important regulators of gene expression. Several related crosslinking-based, high-throughput sequencing methods, including PAR-CLIP, have recently been developed to determine direct binding sites of global protein-RNA interactions. However, no s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053780/ https://www.ncbi.nlm.nih.gov/pubmed/24393468 http://dx.doi.org/10.1186/gb-2014-15-1-r2 |