DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus

BACKGROUND: DNA methylation is of pivotal importance during development. Previous genome-wide studies identified numerous differentially methylated regions upon differentiation of stem cells, many of them associated with transcriptional start sites. RESULTS: We present the first genome-wide, single-...

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Detalles Bibliográficos
Autores principales: Kaaij, Lucas TJ, van de Wetering, Marc, Fang, Fang, Decato, Benjamin, Molaro, Antoine, van de Werken, Harmen JG, van Es, Johan H, Schuijers, Jurian, de Wit, Elzo, de Laat, Wouter, Hannon, Gregory J, Clevers, Hans C, Smith, Andrew D, Ketting, René F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053812/
https://www.ncbi.nlm.nih.gov/pubmed/23714178
http://dx.doi.org/10.1186/gb-2013-14-5-r50

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