Getting a Grip on piRNA Cluster Transcription

The generation of piRNAs from long primary transcripts requires specialized factors that distinguish these precursors from canonical RNA polymerase II transcripts. Mohn et al. and Zhang et al. provide evidence that in Drosophila melanogaster noncanonical transcription coupled with splicing inhibitio...

Descripción completa

Detalles Bibliográficos
Autores principales: Sapetschnig, Alexandra, Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Preview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053829/
https://www.ncbi.nlm.nih.gov/pubmed/24906143
http://dx.doi.org/10.1016/j.cell.2014.05.022
_version_ 1782320447766921216
author Sapetschnig, Alexandra
Miska, Eric A.
author_facet Sapetschnig, Alexandra
Miska, Eric A.
author_sort Sapetschnig, Alexandra
collection PubMed
description The generation of piRNAs from long primary transcripts requires specialized factors that distinguish these precursors from canonical RNA polymerase II transcripts. Mohn et al. and Zhang et al. provide evidence that in Drosophila melanogaster noncanonical transcription coupled with splicing inhibition differentiates piRNA precursors from mRNAs and ensures their correct processing.
format Online
Article
Text
id pubmed-4053829
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Cell Press
record_format MEDLINE/PubMed
spelling pubmed-40538292014-06-16 Getting a Grip on piRNA Cluster Transcription Sapetschnig, Alexandra Miska, Eric A. Cell Preview The generation of piRNAs from long primary transcripts requires specialized factors that distinguish these precursors from canonical RNA polymerase II transcripts. Mohn et al. and Zhang et al. provide evidence that in Drosophila melanogaster noncanonical transcription coupled with splicing inhibition differentiates piRNA precursors from mRNAs and ensures their correct processing. Cell Press 2014-06-05 /pmc/articles/PMC4053829/ /pubmed/24906143 http://dx.doi.org/10.1016/j.cell.2014.05.022 Text en © 2014 The Authors http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Preview
Sapetschnig, Alexandra
Miska, Eric A.
Getting a Grip on piRNA Cluster Transcription
title Getting a Grip on piRNA Cluster Transcription
title_full Getting a Grip on piRNA Cluster Transcription
title_fullStr Getting a Grip on piRNA Cluster Transcription
title_full_unstemmed Getting a Grip on piRNA Cluster Transcription
title_short Getting a Grip on piRNA Cluster Transcription
title_sort getting a grip on pirna cluster transcription
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053829/
https://www.ncbi.nlm.nih.gov/pubmed/24906143
http://dx.doi.org/10.1016/j.cell.2014.05.022
work_keys_str_mv AT sapetschnigalexandra gettingagriponpirnaclustertranscription
AT miskaerica gettingagriponpirnaclustertranscription

Ejemplares similares