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Enhanced human receptor binding by H5 haemagglutinins

Mutant H5N1 influenza viruses have been isolated from humans that have increased human receptor avidity. We have compared the receptor binding properties of these mutants with those of wild-type viruses, and determined the structures of their haemagglutinins in complex with receptor analogues. Mutan...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaoli, Xiao, Haixia, Martin, Stephen R., Coombs, Peter J., Liu, Junfeng, Collins, Patrick J., Vachieri, Sebastien G., Walker, Philip A., Lin, Yi Pu, McCauley, John W., Gamblin, Steven J., Skehel, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053833/
https://www.ncbi.nlm.nih.gov/pubmed/24889237
http://dx.doi.org/10.1016/j.virol.2014.03.008

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