Cargando…

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

BACKGROUND: We have used a sensitized ENU mutagenesis screen to produce mouse lines that carry mutations in genes required for epigenetic regulation. We call these lines Modifiers of murine metastable epialleles (Mommes). RESULTS: We report a basic molecular and phenotypic characterization for twent...

Descripción completa

Detalles Bibliográficos
Autores principales: Daxinger, Lucia, Harten, Sarah K, Oey, Harald, Epp, Trevor, Isbel, Luke, Huang, Edward, Whitelaw, Nadia, Apedaile, Anwyn, Sorolla, Anabel, Yong, Joan, Bharti, Vandhana, Sutton, Joanne, Ashe, Alyson, Pang, Zhenyi, Wallace, Nathan, Gerhardt, Daniel J, Blewitt, Marnie E, Jeddeloh, Jeffrey A, Whitelaw, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053835/
https://www.ncbi.nlm.nih.gov/pubmed/24025402
http://dx.doi.org/10.1186/gb-2013-14-9-r96