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An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
BACKGROUND: We have used a sensitized ENU mutagenesis screen to produce mouse lines that carry mutations in genes required for epigenetic regulation. We call these lines Modifiers of murine metastable epialleles (Mommes). RESULTS: We report a basic molecular and phenotypic characterization for twent...
Autores principales: | Daxinger, Lucia, Harten, Sarah K, Oey, Harald, Epp, Trevor, Isbel, Luke, Huang, Edward, Whitelaw, Nadia, Apedaile, Anwyn, Sorolla, Anabel, Yong, Joan, Bharti, Vandhana, Sutton, Joanne, Ashe, Alyson, Pang, Zhenyi, Wallace, Nathan, Gerhardt, Daniel J, Blewitt, Marnie E, Jeddeloh, Jeffrey A, Whitelaw, Emma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053835/ https://www.ncbi.nlm.nih.gov/pubmed/24025402 http://dx.doi.org/10.1186/gb-2013-14-9-r96 |
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