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DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes

BACKGROUND: Abnormal epigenetic marking is well documented in gene promoters of cancer cells, but the study of distal regulatory siteshas lagged behind.We performed a systematic analysis of DNA methylation sites connected with gene expression profilesacross normal and cancerous human genomes. RESULT...

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Detalles Bibliográficos
Autores principales:	Aran, Dvir, Sabato, Sivan, Hellman, Asaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053839/ https://www.ncbi.nlm.nih.gov/pubmed/23497655 http://dx.doi.org/10.1186/gb-2013-14-3-r21

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