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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
TopHat is a popular spliced aligner for RNA-sequence (RNA-seq) experiments. In this paper, we describe TopHat2, which incorporates many significant enhancements to TopHat. TopHat2 can align reads of various lengths produced by the latest sequencing technologies, while allowing for variable-length in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053844/ https://www.ncbi.nlm.nih.gov/pubmed/23618408 http://dx.doi.org/10.1186/gb-2013-14-4-r36 |