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HP-1γ Controls High-Affinity Antibody Response to T-Dependent Antigens

In vitro observations suggest a role for the mouse heterochromatin protein 1γ (HP-1γ) in the immune system. However, it has not been shown if and how HP-1γ contributes to immunity in vivo. Here we show that in mice, HP-1γ positively regulates the germinal center reaction and high-affinity antibody r...

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Detalles Bibliográficos
Autores principales: Ha, Ngoc, Pham, Duc-Hung, Shahsafaei, Aliakbar, Naruse, Chie, Asano, Masahide, Thai, To-Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053855/
https://www.ncbi.nlm.nih.gov/pubmed/24971082
http://dx.doi.org/10.3389/fimmu.2014.00271