Seq and CLIP through the miRNA world

High-throughput sequencing of RNAs crosslinked to Argonaute proteins reveals not only a multitude of atypical miRNA binding sites but also of miRNA targets with atypical functions, and can be used to infer quantitative models of miRNA-target interaction strength.

Detalles Bibliográficos
Autores principales: Mittal, Nitish, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053862/
https://www.ncbi.nlm.nih.gov/pubmed/24460822
http://dx.doi.org/10.1186/gb4151
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author Mittal, Nitish
Zavolan, Mihaela
author_facet Mittal, Nitish
Zavolan, Mihaela
author_sort Mittal, Nitish
collection PubMed
description High-throughput sequencing of RNAs crosslinked to Argonaute proteins reveals not only a multitude of atypical miRNA binding sites but also of miRNA targets with atypical functions, and can be used to infer quantitative models of miRNA-target interaction strength.
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spelling pubmed-40538622015-01-25 Seq and CLIP through the miRNA world Mittal, Nitish Zavolan, Mihaela Genome Biol Review High-throughput sequencing of RNAs crosslinked to Argonaute proteins reveals not only a multitude of atypical miRNA binding sites but also of miRNA targets with atypical functions, and can be used to infer quantitative models of miRNA-target interaction strength. BioMed Central 2014 2014-01-25 /pmc/articles/PMC4053862/ /pubmed/24460822 http://dx.doi.org/10.1186/gb4151 Text en Copyright © 2014 Mittal and Zavolan; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Mittal, Nitish
Zavolan, Mihaela
Seq and CLIP through the miRNA world
title Seq and CLIP through the miRNA world
title_full Seq and CLIP through the miRNA world
title_fullStr Seq and CLIP through the miRNA world
title_full_unstemmed Seq and CLIP through the miRNA world
title_short Seq and CLIP through the miRNA world
title_sort seq and clip through the mirna world
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053862/
https://www.ncbi.nlm.nih.gov/pubmed/24460822
http://dx.doi.org/10.1186/gb4151
work_keys_str_mv AT mittalnitish seqandclipthroughthemirnaworld
AT zavolanmihaela seqandclipthroughthemirnaworld

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