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DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
BACKGROUND: DNA epigenetic modifications, such as methylation, are important regulators of tissue differentiation, contributing to processes of both development and cancer. Profiling the tissue-specific DNA methylome patterns will provide novel insights into normal and pathogenic mechanisms, as well...
Autores principales: | Lokk, Kaie, Modhukur, Vijayachitra, Rajashekar, Balaji, Märtens, Kaspar, Mägi, Reedik, Kolde, Raivo, Koltšina, Marina, Nilsson, Torbjörn K, Vilo, Jaak, Salumets, Andres, Tõnisson, Neeme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053947/ https://www.ncbi.nlm.nih.gov/pubmed/24690455 http://dx.doi.org/10.1186/gb-2014-15-4-r54 |
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