Opioid Actions in Primary-Afferent Fibers—Involvement in Analgesia and Anesthesia

Opioids inhibit glutamatergic excitatory transmission from the periphery by activating G-protein coupled opioid receptors in the central terminals of primary-afferent neurons in the spinal substantia gelatinosa, resulting in antinociception. Opioid receptor activation in the peripheral terminals of...

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Detalles Bibliográficos
Autores principales: Kumamoto, Eiichi, Mizuta, Kotaro, Fujita, Tsugumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053959/
http://dx.doi.org/10.3390/ph4020343

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