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Mutations within lncRNAs are effectively selected against in fruitfly but not in human
BACKGROUND: Previous studies in Drosophila and mammals have revealed levels of long non-coding RNAs (lncRNAs) sequence conservation that are intermediate between neutrally evolving and protein-coding sequence. These analyses compared conservation between species that diverged up to 75 million years...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053968/ https://www.ncbi.nlm.nih.gov/pubmed/23710818 http://dx.doi.org/10.1186/gb-2013-14-5-r49 |