GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data

To characterize the genetic variation of alternative splicing, we develop GLiMMPS, a robust statistical method for detecting splicing quantitative trait loci (sQTLs) from RNA-seq data. GLiMMPS takes into account the individual variation in sequencing coverage and the noise prevalent in RNA-seq data....

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Detalles Bibliográficos
Autores principales: Zhao, Keyan, Lu, Zhi-xiang, Park, Juw Won, Zhou, Qing, Xing, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054007/
https://www.ncbi.nlm.nih.gov/pubmed/23876401
http://dx.doi.org/10.1186/gb-2013-14-7-r74

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