Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement

The National Institute for Health and Clinical Excellence (NICE) has thus far relied on historical data and predominantly industry-sponsored trials to provide evidence for venous thromboembolic (VTE) prophylaxis in joint replacement patients. We argue that the NICE guidelines may be reliant on assum...

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Autores principales: Jameson, S. S., Baker, P. N., Deehan, D. J., Port, A., Reed, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Editorial Society of Bone and Joint Surgery 2014
Materias:
Annotation: Thrombosis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054010/
https://www.ncbi.nlm.nih.gov/pubmed/24837005
http://dx.doi.org/10.1302/2046-3758.35.2000225
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author Jameson, S. S.
Baker, P. N.
Deehan, D. J.
Port, A.
Reed, M. R.
author_facet Jameson, S. S.
Baker, P. N.
Deehan, D. J.
Port, A.
Reed, M. R.
author_sort Jameson, S. S.
collection PubMed
description The National Institute for Health and Clinical Excellence (NICE) has thus far relied on historical data and predominantly industry-sponsored trials to provide evidence for venous thromboembolic (VTE) prophylaxis in joint replacement patients. We argue that the NICE guidelines may be reliant on assumptions that are in need of revision. Following the publication of large scale, independent observational studies showing little difference between low-molecular-weight heparins and aspirin, and recent changes to the guidance provided by other international bodies, should NICE reconsider their recommendations? Cite this article: Bone Joint Res 2014;3:146–9.
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spelling pubmed-40540102014-06-17 Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement Jameson, S. S. Baker, P. N. Deehan, D. J. Port, A. Reed, M. R. Bone Joint Res Annotation: Thrombosis The National Institute for Health and Clinical Excellence (NICE) has thus far relied on historical data and predominantly industry-sponsored trials to provide evidence for venous thromboembolic (VTE) prophylaxis in joint replacement patients. We argue that the NICE guidelines may be reliant on assumptions that are in need of revision. Following the publication of large scale, independent observational studies showing little difference between low-molecular-weight heparins and aspirin, and recent changes to the guidance provided by other international bodies, should NICE reconsider their recommendations? Cite this article: Bone Joint Res 2014;3:146–9. British Editorial Society of Bone and Joint Surgery 2014-05-01 /pmc/articles/PMC4054010/ /pubmed/24837005 http://dx.doi.org/10.1302/2046-3758.35.2000225 Text en ©2014 The British Editorial Society of Bone & Joint Surgery ©2014 The British Editorial Society of Bone & Joint Surgery. This is an open-access article distributed under the terms of the Creative Commons Attributions licence, which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited.
spellingShingle Annotation: Thrombosis
Jameson, S. S.
Baker, P. N.
Deehan, D. J.
Port, A.
Reed, M. R.
Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title_full Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title_fullStr Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title_full_unstemmed Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title_short Evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
title_sort evidence-base for aspirin as venous thromboembolic prophylaxis following joint replacement
topic Annotation: Thrombosis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054010/
https://www.ncbi.nlm.nih.gov/pubmed/24837005
http://dx.doi.org/10.1302/2046-3758.35.2000225
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